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Superior HPLC columns

The manufacturer, Nacalai Tesque, Inc. has more than 160-year long presence in Kyoto, the ancient capital of Japan.

Based on spherical, totally porous silica, COSMOSIL columns provide enhanced chemical and mechanical stability as well as very high surface coverage.
COSMOGEL packing materials are non-silica based and provide superior performance in ion exchange columns.

Cosmosil phases

  Functional Group Particle, um USP Carbon load, % Link
SL-II Si 3, 5, 15 L3 - click to follow
HIC Si 5 - - click to follow
CNT Si 5 - - click to follow
TMS-MS C1 5 L13 5 click to follow
C4-MS C4 5 L26 7 click to follow
C4-AR-300 C4 5 L26 6 click to follow
C8-MS C8 5 L7 10 click to follow
C8-AR-300 C8 5 L7 7 click to follow
C18-EB C18 3 L1 n/a click to follow
C18-MS-II C18 2.5, 5, 15 L1 16 click to follow
C18-AR-II C18 3, 5, 15 L1 n/a click to follow
C18-PAQ C18 (AQ) 3, 5, 15 L1 n/a click to follow
Protein-R C18 5 - n/a click to follow
C18-AR-300 C18 5 L1 12 click to follow
HILIC triazole 2.5, 5 - n/a click to follow
PBr pentabromobenzyl 5 - 8 click to follow
C22-AR-II C22 5 - 19 click to follow
Ph-AR-300 phenyl 5 L11 7 click to follow
PE-MS phenyl-ethyl 5 L11 10 click to follow
CN-MS CN 5 L10 7 click to follow
NH2-MS NH2 5 - n/a click to follow
Sugar-D secondary/tertiary amine 5 - n/a click to follow
DIOL-120-II DIOL 5 L20 n/a click to follow
DIOL-300-II DIOL 5 L20 n/a click to follow
DIOL-1000-II DIOL 5 L20 n/a click to follow
Cholester cholesteryl 2.5, 5 - n/a click to follow
πNAP naphthyl-ethyl 2.5, 5 - n/a click to follow
PYE pyrenyl-ethyl 5 - n/a click to follow
NPE nitrophenyl-ethyl 5 - n/a click to follow
PBB-R pentabromobenzyl 5 - n/a click to follow
Buckyprep pyrenyl-propyl 5 - n/a click to follow
Buckyprep-D nitrocarbazoyl 5 - n/a click to follow
Buckyprep-M phenothiazinyl 5 - n/a click to follow

 

 

Cosmosil SFC phases

  Functional Group Pore, A Particle, um Link
HP 3-Hydroxyphenyl group 120 3, 5 click to follow
PY Pyridinyl group  120 3, 5 click to follow
Quinoline Quinoline group 130 / 120 2.5 / 5 click to follow
Cholester Cholesteryl group 130 / 120 2.5 / 5 click to follow
PBr Pentabromobenzyl group  120 5 click to follow

 

 

Cosmosil chiral phases

  Functional Group USP Particle, um Link
Chiral A Amylose tris (3,5-dimethylphenyl carbamate) L99 3, 5 click to follow
Chiral B Cellulose tris (3,5-dimethylphenyl carbamate)   3, 5 click to follow
Chiral C Cellulose tris (3,5-dichlorophenyl carbamate)   3, 5 click to follow

 

 

Cosmogel phases

  Functional Group Particle, um USP Carbon load, % Link
COSMOGEL IEX Q anion exchange 5 - - click to follow
COSMOGEL IEX Q-N anion exchange 5 - - click to follow
COSMOGEL IEX S cation exchange 5 - - click to follow
COSMOGEL IEX S-N cation exchange 5 - - click to follow
COSMOGEL IEX M amphoteric 5 - - click to follow
COSMOGEL IEX M-N amphoteric 5 - - click to follow

 

 

 

 

Downloads

News

Cosmosil chiral immobilized phases, 3 or 5um
Cosmosil chiral brochure
Cosmocore: new 2.6um fused-core particles -C18, Cholester and PBr (Pentabromobenzyl)
Cosmocore brochure
Cosmosil 3C18-EB: Excellent for Basic compounds
Cosmosil 3C18-EB brochure

Catalogs

Cosmosil HPLC Catalog 2019
Cosmosil HPLC Catalog 2017
Cosmosil HPLC Catalog 2015

Cosmosil HILIC Application Notebook
Cosmosil / Cosmocore Cholester Application Notebook
Cosmosil / Cosmocore Technical Notes
                    - Preparation of mobile phases;   Guard column selection
                    - Sample pretreatment;   Method development;   Troubleshooting

Brochures

Cosmosil RP Phase Selectivities
Preparation of mobile phase for HPLC
Cosmosil ODS phases (MS-II, AR-II, PAQ)
Cosmosil C18-PAQ
Cosmosil 3.0mm ID columns (MS-II, AR-II, PAQ)
Cosmosil UHPLC columns (MS-II, Cholester, πNAP)
Cosmo(+) capillaries for CE (Capillary Electrophoresis)
Cosmosil special columns (Cholester, πNAP, PYE, HILIC, Protein-R, Sugar-D)
Cosmosil Cholester columns
Cosmosil πNAP columns
Cosmosil PYE and NPE columns
Cosmosil HILIC columns
Cosmosil 2.5um HILIC columns
Cosmosil HILIC chromatograms
Cosmosil PBr columns
Cosmosil Protein-R columns
Cosmosil Sugar-D columns
Cosmosil PBB-R columns
Cosmosil Buckyprep and PBB columns
Cosmosil Buckyprep-D brochure
Cosmosil CNT (Carbon NanoTube) columns
Cosmosil DIOL-II columns
Cosmosil SL-II columns
Cosmosil bulk sorbents for prep. chromatography
Cosmogel IEX series columns
Cosmosil SFC brochure
Cosmosil Technical Guide for SFC Columns

Applications, Chromatograms

Antibiotics Analyses
Vitamin Analyses
Fatty Acids Analyses
Polyphenols Analyses
Food Additives Analyses
Toxic Food Contaminants Analyses
Saccharides Analyses
Rare Sugars Analyses
Purification with Cosmogel IEX Type Q columns (Trypsin Inhibitor from Soybean)
Analysis of DEHP (Bis(2-ethylhexyl)phthalate)
Food samples analyses with Cosmosil Sugar-D columns
Fullerene chromatogram index
Cosmosil HILIC - Melamine Analysis
Cosmosil πNAP - Tocopherol Analysis

 

Useful links

Cosmosil UHPLC Columns
Cosmosil Wide-Pore (300A) Columns
Cosmogel NEW ion-exchange (IEX) Columns
Cosmosil online Applications Guide (ver1)
Application data (Japanese Pharmacopeia 1)
Application data (Japanese Pharmacopeia 2)