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Evosphere monodisperse HPLC particles

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Manufacture of silica is at the core of our business, producing the very latest surfaces to which we then add our innovative bonding chemistries. Full control of silica processes allows the ability to scale from UHPLC 1.7um particles upto 10um preparative scale particles.

Fortis phases

Phase Functional group Endcapped Particle, um Pore, A Carbon, %
BIO C4 C4 Yes 1.7, 5 300 5
C8 C8 Yes 1.7, 3, 5, 10 100 13
C18 C18 Yes 1.7, 2.5, 3, 5, 10 100 17
H2O (aqueous) C18 Yes 1.7, 3, 5, 10 100 18
BIO C18 C18 Yes 1.7, 5 300 11.5
UniverSil C18 C18 Yes 3, 5 140 11
UniverSil HS C18 C18 Yes 3, 5 100 16
Diphenyl Diphenyl Yes 1.7, 2.5, 3, 5 100 13
CN CN Yes 1.7, 3, 5 100 7
NH2 NH2 Yes 1.7, 3, 5 100 5
HILIC Si No 1.7, 3, 5 100 n/a
HILIC DIOL DIOL No 1.7, 3, 5 100 4

 

 

Fortis SpeedCore phases

Phase Functional group USP Particle, um Pore, A Carbon, %
C8 C8 L7 2.6, 5 80 5
C18 C18 L1 2.6, 5 80 10
C18 pH Plus (pH 1 - 12) C18 L1 2.6, 5 80 10
AQUA C18 L1 2.6, 5 80 7
C18-PFP C18-PFP --- 2.6, 5 80 n/a
Diphenyl Diphenyl L11 2.6, 5 80 7
PFP PentaFluoroPhenyl L43 2.6, 5 80 6
HILIC Si L3 2.6, 5 80 n/a
RP18-Amide C18-Amide L60 2.6, 5 80 n/a

 

Fortis SpeedCore BIO phases

Phase Functional group USP Particle, um Pore, A Carbon, %
Peptide C18 C18 L1 2.6 160 6
Protein C18 C18 L1 3.5 300 4
Protein C8 C8 L7 3.5 300 3
Protein C4 C4 L26 3.5 300 2

 

2.6um particles incorporate a 1.8um solid core, with a 0.4um outer porous shell. 5um particles incorporate a 4.0um solid core, with a 0.4um outer porous shell.

 

Fortis PACE

Fortis PACE

Fortis PACE columns are an optimised design specifically for the needs of High Throughput Screening (HTS).
Short columns lengths (20 or 30mm), high efficiency and resolution.
Fortis PACE columns contain any stationary phase from the Fortis range and are specifically designed for HTS, whether isocratic or ballistic gradients. Optimised packing density in the low volume hardware leads to ultra sharp peak shapes combined with maximum efficiency. By combining a low volume flow path with an optimised frit Fortis PACE columns provide improved efficiency, asymmetry and pressure. 

 

2022 summer - Fortis Technologies has launched a brand new family of columns, unique on the market, and characterized by the highest technology used in the design and production of HPLC phases:
EVOSPHERE

EVOSPHERE columns guarantee the best resolution of compounds and are available in a wide range of phases.

Evosphere monodisperse particles

 

Fortis Evosphere columns 

Fortis Evosphere phases

Phase USP Particle, um Pore, A Carbon, % pH 
Evosphere C12 L87 1.7, 3, 5 100 17 1 - 9
Evosphere  C18-AR L1 1.7, 3, 5  100  17  2 - 9
Evosphere C18-PFP  L1 1.7, 3, 5  100  17  2 - 9
Evosphere RP18-Amide  L60 1.7, 3, 5  100  20  2 - 9
Evosphere Phenyl-Hexyl  L11 1.7, 3, 5  100  14  2 - 9
Evosphere Diphenyl  L11 1.7, 3, 5  100  15  2 - 9
Evosphere PFP  L43 1.7, 3, 5  100  13  2 - 9
Evosphere  AQUA L96 1.7, 3, 5  100  18  2 - 9

Based on completely porous monodisperse particles, they ensure a series of advantages such as:
- high efficiency
- high load capacity
- scalable to the Prep version
- low back pressure
- surface area of ​​350 m2/g, guarantee of good retention
The low particle size dispersion leads to a better packing of the columns and consequently to a very high efficiency for a completely porous silica particle.
The C18-PFP and C18-AR phases fall into the L1 category of Pharmacopeia, and can therefore be used to obtain unique selectivity.
The greater selectivity is also essential to obtain an optimal resolution of the critical pairs of compounds.
All columns are individually tested to ensure best reproducibility and robustness.