Kromasil
High pore volume and surface area and very high mechanical stability - even today this
combination of properties is unmatched by other chromatography packings on the market.
Kromasil and Kromasil Chiral are premium, silica-based HPLC packings, developed by Separation Products at Eka Chemicals. Reduced levels of Na, K, Ca, Fe, Al, and Mg make Kromasil packing materials useful for polar compounds which tend to interact with the silica surface. The wide range of particle sizes is an essential consideration for scale-up. The pH stability for bonded phases is 1.5 - 9.5
Kromasil phases
| Phase | Functional Group | Endcapped | Particle, um | Pore, A |
| Silica | - | - | 3.5, 5, 7, 10, 13, 16 | 60, 100, 300 |
| C4 | C4 | Yes | 1.8, 2.5, 3.5, 5, 7, 10, 13, 16 | 100, 300 |
| C8 | C8 | Yes | 1.8, 2.5, 3.5, 5, 7, 10, 13, 16 | 100, 300 |
| C18 | C18 | Yes | 1.8, 2.5, 3.5, 5, 7, 10, 13, 16 | 100, 300 |
| Eternity C18 | C18 | Yes | 2.5, 5 | 100 |
| EternityXT C18 | C18 | Yes | 1.8, 2.5, 5, 10 | 100 |
| Eternity PhenylHexyl | Phenyl / Hexyl | Yes | 2.5, 5 | 100 |
| EternityXT PhenylHexyl | Phenyl / Hexyl | Yes | 1.8, 2.5, 5, 10 | 100 |
| Phenyl | Phenyl | Yes | 5, 10, 16 | 100 |
| NH2 | NH2 | Yes | 5, 10 | 100 |
| CN | CN | No | 5, 10 | 60 |
| DIOL | DIOL | No | 5, 10 | 60 |
| HILIC-D | DIOL | No | 5 | 60 |
| Chiral | CHI-DMB | - | 5, 10, 16 | |
| Chiral | CHI-TBB | - | 5, 10, 16 | |
| Chiral | AmyCoat | AmyCoat-RP | 3, 5, 10, 25 | |
| Chiral | CelluCoat | CelluCoat-RP | 3, 5, 10, 25 |
Kromasil columns and bulk phases
| Kromasil 60A | 1.8um | 2.5um | 3.5um | 5um | 7um | 10um | 13um | 16um | 25um |
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| Kromasil 100A | 1.8um | 2.5um | 3.5um | 5um | 7um | 10um | 13um | 16um | 25um |
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| Kromasil 300A | 1.8um | 2.5um | 3.5um | 5um | 7um | 10um | 13um | 16um | 25um |
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| Kromasil chiral | 1.8um | 2.5um | 3um | 5um | 7um | 10um | 13um | 16um | 25um |
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| CelluCoat |
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| Kromasil core-shell | 1.8um | 2.5um | 3um | 5um | 7um | 10um | 13um | 16um | 25um |
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| C18-EternityShell |
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packed columns ONLY
columns and ALSO bulk sorbents
Bulk prep sorbents
Bulk sorbents are available in quantity of 200g, 500g, 1kg and 2kg.
Kromasil HPLC silica consists of perfectly spherical, totally porous particles. The uniqueness of Kromasil high performance spherical silica is the combination of:
- high surface area
- mechanical strength
- chemical purity
- chemical stability
- optimized surface
properties
- well-defined pore
structure
Kromasil chiral stationary phases
are based on the well-known Kromasil premium spherical silica. The chiral
polymer is covalently bonded to the functionalized Kromasil silica. Two
phases have been developed to complement each other in selectivity:
Kromasil CHI-DMB: The chiral monomer is 0,0'-bis
(3,5-dimethylbenzoyl)-N,N'-diallyl-L-tartar diamide.
Kromasil CHI-TBB: The chiral monomer is 0,0'-bis
(4-tert-butylbenzoyl)-N,N'-diallyl-L-tartar diamide.
The new CelluCoat and AmyCoat chiral phases are based on a super-wide pore silica matrix developed in-house, and coated with a functionalized cellulose selector. High resolution, excellent selectivity, high pressure stability and stable performance when switching between compatible mobile phases are some important benefits. CelluCoat is equivalent to Chiralcel OD, AmyCoat is equivalent to Chiralpak AD of Daicel.
Test Chromatograms
see
Downloads ... Chiral separations
News
Kromasil diC4 stationary phase
for biomolecule separations
Kromasil C18(w): fully
wettable HPLC phase for polar compounds
Kromasil diC4 Brochure
Kromasil C18(w) Brochure
Kromasil SFC columns
...... delivered in cyano, diol, silica, and
2-ethylpyridine chemistries
Kromasil SFC Brochure
Kromasil Eternity long-life columns
Vary the pH
from 1 to 12, repeatedly ... run at high temperatures,
part of the time or all the time ....
Kromasil Eternity Brochure
Kromasil Eternity XT C18 10um
Prep Brochure
Kromasil Eternity C18 and PhenylHexyl Columns: Presentation (pdf file)
Kromasil UHPLC columns
1.8um
and 2.5um (100A) C4, C8 and C18 plases
Kromasil 1.8um UHPLC columns
Kromasil 2.5um UHPLC columns
Kromasil core-shell columns
Kromasil ClassicShell Brochure
Kromasil
EternityShell Brochure
Catalogs, Brochures
Kromasil Classic Columns
Kromasil Product Catalogue
Kromasil Application Guide
Kromasil HILIC-D Brochure
Chiral Separations
Kromasil Chiral Brochure
Kromasil Chiral Stationary Phases
Kromasil AmyCoat and
CelluCoat Chiral Stationary Phases Data Sheet
Kromasil AmyCoat and
CelluCoat: New Polysaccharide-based Chiral Stationary Phases
Kromasil AmyCoat and CelluCoat Application Guide
Kromasil
AmyCoat 3um: Rapid and Efficient Chiral Separations
Kromasil AmyCoat Test
Chromatogram
Kromasil CelluCoat Test
Chromatogram
Kromasil Chiral DMB and TBB
Kromasil Chiral DMB and
TBB Application Guide
Chiral SFC Separations Using
Different Polysaccharide Based Stationary Phases
Peptides and Proteins Separations
Kromasil 300A: for
your Protein Separations
RP Separation of Peptides and
Proteins
HPLC Purification of
Peptides (I)
HPLC Purification of
Peptides (II)
Preparative Separations
Kromasil Preparative Sorbents
Loadability in Preparative
Chromatography
Chiral
Preparative Separations using Coated Polysaccharide Stationary Phases
Preparative Peptide
Separations
Posters, Presentations
Kromasil Eternity C18: Designed
for Long Life
Kromasil Phenyl with High Ligand
Coverage
Kromasil DIOL with High Ligand Coverage
RP Chromatography at Elevated pH
(I)
RP Chromatography at elevated pH (II)
The Good RP HPLC Stationary
Phases
Cross references to Kromasil products
