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Charge-modulated HILIC columns

Complementary selectivity for polar / hydrophilic analytes

iHILIC columns are designed for the separation and purification of polar and hydrophilic compounds using Hydrophilic Interaction Liquid Chromatography (HILIC). The packed stationary phases are charge-modulated amide silicas which are covalently bonded with neutral, positively charged, and negatively charged hydrophilic functional groups. The separation mechanism with iHILIC columns is based on a combination of hydrophilic interaction, hydrogen bonding, and weak electrostatic interactions. They have unique separation selectivity and high separation efficiency.

iHILIC-Fusion
iHILIC-Fusion

 

Charge-modulated Hydroxyethyl Amide HILIC columns

  • UHPLC and HPLC
  • silica based, 1.8, 3.5 and 5um 
  • available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
  • high efficiency and ultra-low bleeding
iHILIC-Fusion(+)
iHILIC-Fusion(+)

 

Charge-modulated Hydroxyethyl Amide HILIC Columns

  • UHPLC and HPLC, with enhanced retention for anions
  • silica based, 1.8, 3.5 and 5um 
  • available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
  • high efficiency and ultra-low bleeding
iHILIC-Fusion(P)
iHILIC-Fusion(P)

 

Charge-modulated Amide HILIC columns

  • polymer-based, 5um 
  • available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
  • stable at pH 1-10
  • ultra-low bleeding
iHILIC-(P) Classic
iHILIC-(P) Classic

 

Charge-modulated DIOL HILIC columns

  • polymer-based, 5um 
  • available in PEEK, stainless steel (SS), or PEEK-lined SS (PEEK-SS)
  • stable at pH 1-10
  • ultra-low bleeding