Inertsil

 

News

ACE HILIC - three chemistries available

01 July, 2017

more info ....

Promotion

ACE Method Development Kits:
3 columns for the price of 1

more info ....

Events

HTC-15 (Cardiff, Wales)

24-26 January, 2018

more info ....

"...we look forward to serving the

separations industry with the finest

and most useful products"

For new methods, we recommend trying the 3-Series and 4-Series products

The original 2-Series Inertsil phases, including Silica, C4, C8, ODS-2 and Phenyl, created the high purity silica revolution in the late 1980s. ODS-80A was originally introduced to provide a higher surface area alternative to ODS-2, but with the same inertness and base-deactivated properties. These columns remain some of the most useful and popular on the market today, even though Inertsil 3-Series and 4-Series phases are a major advancement on the original 2-Series: the silica purity was increased, the chemical and physical stability of the silica was enhanced, and the bonding and end capping were optimized to create more deactivated phases.

Inertsil phases

Phase Functional Group Endcapped Particle, um Pore, A
Series-2        
Silica-150A - - 5 150
C4 C4 Yes 5 150
C8 C8 Yes 5 150
ODS-2 C18 Yes 5 150
Phenyl Phenyl  Yes 5 150
         
Series-3        
Silica-100A - - 3, 5 100
C8-3 C8 Yes 2, 3, 5, 10 100
ODS-3 C18 Yes 2, 3, 4, 5, 10 100
ODS-3V C18 Yes 3, 5 100
ODS-P C18 Yes 3, 5 100
ODS-EP C18 No 5 100
ODS-SP C18 Yes 3, 5 100
Peptides C18 C18 Yes 4 100
Sulfa C18 C18 Yes 3, 5 100
Phenyl-3 Phenyl No 2, 3, 5 100
NH2 NH2 No 3, 5 100
CN-3 CN No 3, 5 100
DIOL DIOL No 3, 5 100
HILIC Alkyl Diol No 3, 5 100
Amide (HILIC) Carbamoyl No 3, 5 100
AX Diethylaminoethyl No 5 100
CX Propylbenzenesulfonyl No 5 100
Series-4        
C8-4 C8 Yes 2, 3, 5 100
ODS-4 C18 Yes 2, 3, 5 100
ODS-4V C18 Yes 3, 5 100
InertSustain C8 C8 Complete 3, 5 100
InertSustain C18 C18 Complete 2, 3, 5 100
InertSustain AQ-C18 C18 Complete 1.9, 3, 5 100
InertSustain Phenyl Phenyl No 3, 5 100
InertSustain PhenylHexyl Phenyl-Hexyl Yes 3, 5 100
InertSustain NH2 NH2 No 3, 5 100
WP (wide-pore) 300A        
Silica-300A - - 5 300
C4-300A C4 No 5 300
C8-300A C8 Yes 5 300
C18-300A C18 Yes 5 300
DIOL-300A DIOL  No 5 300
Preparative        
Prep-SIL - - 10 100
Econo Prep-SIL - - 40 80
Prep-C8 C8 Yes 10 100
Prep-ODS C18 Yes 10 100
Econo Prep-ODS C18 Yes 40 80
Misc.        
ODS (classic) C18 Yes 5, 10 100
ODS-80A C18 Yes 5 80
Titansphere TiO2 No 5 100
Bioptic AV1 and AV-2 Glycoprotein bonded silica - 5 -

 

 

Columns and applications

Type Column Features



RP
InertSustain C18 Highly inert and durable ODS column compatible with wide pH range
Inertsil ODS-4 Highly inert ODS column with moderate retentivity
Inertsil ODS-4V Highly inert ODS column available for validation
Inertsil ODS-3 ODS column offering high inertness and retentivity
Inertsil ODS-3V ODS column available for validation
Inertsil ODS-SP ODS column for rapid analysis of hydrophobic compounds
Inertsil ODS-P Polymeric ODS column (C18 group polymerically bonded to silica gel)
Inertsil ODS-EP Polar group embedded ODS column
Inertsil WP300 C18 Inert and durable ODS column for analysis of large molecules (e.g. proteins)
Inertsil Peptides C18 ODS column designed for peptide mapping
Inertsil Sulfa C18 ODS column designed for analysis of sulfa drugs
Inertsil ODS-2 ODS column employed pore-size 150A silica gel
Inertsil ODS-80A ODS column made with narrow pore (80A) silica gel
Inertsil ODS The original ODS column of Inertsil Series
InertSustain C8 Highly inert and durable C8 column compatible with wide pH range
Inertsil C8-4 Highly inert C8 column offering weak retentivity
Inertsil C8-3 C8 column offering high inertness and retentivity
Inertsil WP300 C8 Inert and durable C8 column for anyalysis of large molecules (e.g. proteins)
Inertsil C8 C8 column employed pore-size 150A silica gel
Inertsil C4 C4 column offering weak retentivity
Inertsil WP300 C4 Polar group embedded  C4 column for analysis of hydrophobic proteins
InertSustain Phenyl Phenyl column offering pi-pi interactions and shape selectivity
Inertsil Ph-3 Phenyl column offering strong pi-pi interactions
Inertsil Ph Standard phenyl column
Inertsil PREP-ODS ODS column for preparative HPLC (particle size : 10um)
Inertsil PREP-C8 C8 column for preparative HPLC (particle size : 10um)
Inertsil Econo PREP-ODS ODS column for large-amount preparative HPLC (particle size : 40um)


HILIC
Inertsil HILIC HILIC column (diol group bonded phase)
Inertsil Amide Amide column for HILIC separation
InertSustain NH2 Highly durable amino column available for sugar analysis
Inertsil NH2 Amino column offering strong retentivity




NP
Inertsil Diol DIOL column (also available as SEC column)
Inertsil SIL-100A Ultra Pure Silica gel with pore size 100A
Inertsil SIL-150A Ultra Pure Silica gel with pore size 150A
Inertsil WP300 SIL Ultra pure Silica gel with wide pore size 300A
Inertsil CN-3 Cyano column offering pi-pi interactions and hydrogen bonding interactions
Inertsil PREP-SIL Pure silica column for preparative HPLC (particle size : 10um)
Inertsil Econo PREP-SIL Pure silica column for large-amount preparative HPLC (particle size : 40um)
SEC Inertsil WP300 Diol SEC column for various size of molecules (also available in normal and reversed phase mode)

IE
Inertsil AX Strong Anion Exchange column
Inertsil CX Strong Cation Exchange column

Misc.
Titansphere TiO Alternative material to silica gel (retains phosphorylated compounds selectively)
Bioptic AV-1, AV-2 Avidin column available for pharmacokinetic study

 

Quick access to the most important applications

Inertsil Series-2 phases (all) A vast collection of chromatographic applications data.
Inertsil Silica-100A (the silica base of Inertsil Series-3 phases) Parabenes
Inertsil C8-3 Amitriptyline, Dipyridamole, Butylphenols, Vitamins, Phthalates
Inertsil C8-4 The most deactivated C8 columns ever made.
Inertsil ODS-3 Azo dyes, Flavonoids, Fungicides
Inertsil ODS-3V ODS-3V is delivered with a Manufacturer's Validation Certificate showing the detailed results of every QA and QC step in manufacturing.
Inertsil ODS-4 The No. 1 recommended column when new method is developed.
Inertsil ODS-P The polymerically bonded ODS-P phase has unique selectivity for planar compounds, designed for the analysis of 16 priority PAHs in environmental samples but has also found to be useful for pharmaceutical analysis of planar compounds.
Inertsil ODS-EP Inertsil ODS-EP contains a polar functional group embedded between the silica surface and the C18 group. The embedded polar group makes the C18 phase stable in 100% aqueous eluents without "phase collapse."
Inertsil ODS-Sprint ODS-Sprint is super base deactivated and optimally bonded phase to retain polar compounds without excessive retention of non-polar compounds.
Inertsil Sulfa C18 Sulfonamides
Inertsil Phenyl-3 Aflatoxins, Preservatives
Inertsil NH2 Inertsil NH2 columns are bonded in a manner which does not lead to anomer resolution in sugar analyses because the primary amino groups are not modified.  This leads to more accurate qualitative and quantitative results.
Inertsil CN-3 A super high density bonding procedure has produced a CN phase that eliminates the instability and irreproducibility that plagued standard CN phases.  CN-3 offers unique selectivity, long column operating life, and excellent peak shapes in both reverse phase and normal phase modes.
Inertsil DIOL In normal phase mode, the diol phase provides an alternative selectivity to silica, often with increased retentivity which helps improve separating power. In reverse phase mode, compounds such as amino acids and water-soluble vitamins are nicely separated with unique selectivity with simple eluents.
Inertsil HILIC HILIC was developed as an alternative to reverse phase chromatography for polar compounds.
Inertsil WP 300A columns Protein and peptide analyses.