Nucleosil
An absolutely reliable choice in HPLC
Nucleosil is available in a wide range of pore sizes. Nucleosil 100Å has the greater capacity whilst the 120Å material exhibits the lower column back pressure. The 300A silica columns are used for bioanalytical separations.
Nucleosil phases
| Phase | Modification | Formula |
| RP phases | ||
| NUCLEOSIL C18 | medium density octadecyl, endcapped | -(CH2)17-CH3 |
| NUCLEOSIL C18 AB | crosslinked octadecyl, endcapped, high steric selectivity | -(CH2)17-CH3 |
| NUCLEOSIL C18 HD | high density octadecyl, endcapped | -(CH2)17-CH3 |
| NUCLEOSIL C18 Nautilus | hydrophilic octadecyl, embedded polar group, endcapped | -(CH2)17-CH3 |
| NUCLEOSIL Protect I | special RP phase with protective polar group, endcapped | |
| NUCLEOSIL C8 ec | medium density octyl, endcapped | -(CH2)7-CH3 |
| NUCLEOSIL C8 | standard octyl, not endcapped | -(CH2)7-CH3 |
| NUCLEOSIL C8 HD | high density octyl, endcapped | -(CH2)7-CH3 |
| NUCLEOSIL C4 | medium density butyl, endcapped | -(CH2)3-CH3 |
| NUCLEOSIL C2 | dimethyl | -(CH3)2 |
| NUCLEOSIL C6H5 ec | medium density phenyl, endcapped | -(CH2)3-C6H5 |
| NUCLEOSIL C6H5 | standard phenyl, not endcapped | -(CH2)3-C6H5 |
| Polar phases | ||
| NUCLEOSIL CN | cyanopropyl (nitrile) | -(CH2)3-CN |
| NUCLEOSIL NO2 | nitrophenyl | -(CH2)3-C6H4-NO2 |
| NUCLEOSIL OH | diol (dihydroxypropyl) | -(CH2)3-O-CH2-CH(OH)-CH2OH |
| NUCLEOSIL NH2 | aminopropyl | -(CH2)3-NH2 |
| NUCLEOSIL N(CH3)2 | dimethylamino | -(CH2)3-N(CH3)2 |
| NUCLEOSIL SA | benzenesulphonic acid, strongly acidic cation exchanger (SCX) | -(CH2)3-C6H4-SO3Na |
| NUCLEOSIL SB | quaternary ammonium, strongly basic anion exchanger (SAX) | -(CH2)3-C6H4-CH2-N+(CH3)3Cl– |
| NUCLEOSIL SiOH | unmodified | (SiO2)n |
The Hichrom manufactured Nucleosil columns use standard compression fittings.
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 GUARD CARTRIDGE SYSTEM (JPEG file, opens in new window) |
