Cogent
State-of-the-Need products at exceptional value
Using a special technology, the ligands are bonded directly to the TYPE-C silica surface with two separate points of attachment for extreme durability even at very low pH (1.0). This combination gives very stable, efficient and unique HPLC columns that have a wider range of compounds to be separated. Since there are virtually no silanols and the silica surface is slightly hydrophobic, these columns can be used with 100% aqueous mobile phases.
Cogent (Type-C silica-based) phases
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| Silica-C | - | - | 2.2 / 4 | 120 / 100 | - |
| Diamond Hydride | proprietary | - | 2.2 / 4 | 120 / 100 | 2 |
| Bidentate C8 | C8 | No | 2.2 / 4 | 120 / 100 | 11 - 14 |
| Bidentate C8 300 | C8 | No | 5 | 300 | 5.0 |
| Bidentate C18 | C18 | No | 2.2 / 4 | 120 / 100 | 18 - 20 |
| Phenyl Hydride | Phenyl | No | 2.2 / 4 | 120 / 100 | 9 - 12 |
| UDA | Undecanoic acid | No | 2.2 / 4 | 120 / 100 | 14 - 15 |
| UDC-Cholesterol | Alkyl-cholesterol | No | 2.2 / 4 | 120 / 100 | 13 - 14 |
Cogent (Thermally Treated Sol-Gel-Type-B silica-based) phases
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| C27 | C27 | Yes | 5 | 120 | 17 |
| C30 | C30 | No | 3 / 5 | 200 | 18 |
| HPS High-Performance Columns | |||||
| HPS-C8 | C8 | Yes | 5 | 120 | 11.5 |
| HPS-C18 | C18 | Yes | 5 | 120 | 18.5 |
| HPS-CN | cyano | Yes | 5 | 120 | 7.5 |
| HPS-NH2 | Amino | No | 5 | 120 | 4.1 |
| HPS-Phenyl | Phenyl | No | 5 | 120 | 12 |
HILIC columns vs. Cogent Type-C silica-based columns
Cogent Type-C columns in ANP (Aqueous Normal Phase) mode
outperform HILIC columns in the following areas:
- retain nonpolar compounds by RP mechanism
- retain polar compounds by NP mechanism
- BOTH RP and NP mechanisms can operate simultaneously
- can separate samples with BOTH polar and nonpolar analytes
- equilibration time for gradient elution is 5 minutes between runs
News
Cogent Diamond Hydride column
separates Vancomycin using a simple gradient with water, acetonitrile, and
formic acid.
Vancomycin - retention of a
highly polar antibiotic
Cogent Phenyl Hydride columns:
unique selectivity for compounds with aromatic rings with all the TYPE-C silica
benefits. These columns can be used in RP, ANP or NP mode and changed back and forth
without damage to the columns.
Orthogonal Assay for Fluoxetine
Catalog
Brochures
A new technology that saves you
time and money
Cogent Type-C Silica-Based Bonded
Stationary Phases - Quick Start Instructions
Applications
Pharmaceutical
Applications
Clinical
Applications
Environmental and
Food
Applications
Type-C silica
Type-C silica
Cogent Silica-C
Cogent Diamond Hydride
Cogent Bidentate C18
Cogent UDC-Cholesterol
