Cogent
State-of-the-Need products at exceptional value
Using a special technology, the ligands are bonded directly to the TYPE-C silica surface with two separate points of attachment for extreme durability even at very low pH (1.0). This combination gives very stable, efficient and unique HPLC columns that have a wider range of compounds to be separated. Since there are virtually no silanols and the silica surface is slightly hydrophobic, these columns can be used with 100% aqueous mobile phases.
Cogent C (Type-C Silica based) phases
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| Silica-C | - | - | 4 | 100 | - |
| Silica-C 2.0 | - | - | 2.2 | 120 | - |
| DIOL | DIOL | - | 4 | 100 | 9 - 10 |
| DIOL 2.0 | DIOL | - | 2.2 | 120 | 9 - 10 |
| Amide | Amide | - | 4 | 100 | 2 - 3 |
| Diamond Hydride | proprietary | - | 4 | 100 | >0.5 |
| Diamond Hydride 2.0 | proprietary | - | 2.2 | 120 | 2 |
| Bidentate C8 | C8 | - | 4 | 100 | 13 - 14 |
| Bidentate C8 2.0 | C8 | - | 2.2 | 120 | 11 - 12 |
| Bidentate C8 300 | C8 | - | 5 | 300 | 5 |
| Bidentate C18 | C18 | - | 4 | 100 | 18 - 19 |
| Bidentate C18 2.0 | C18 | - | 2.2 | 120 | 20 |
| Phenyl Hydride | Phenyl | - | 4 | 100 | 10 - 12 |
| Phenyl Hydride 2.0 | Phenyl | - | 2.2 | 120 | 9 - 10 |
| UDA | Undecanoic acid | - | 4 | 100 | 14 - 15 |
| UDA 2.0 | Undecanoic acid | - | 2.2 | 120 | 14 - 15 |
| UDC-Cholesterol | Alkyl-cholesterol | - | 4 | 100 | 13 - 14 |
| UDC-Cholesterol 2.0 | Alkyl-cholesterol | - | 2.2 | 120 | 13 - 14 |
Cogent HPS (High Purity Silica based) phases
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| HPS-Silica | Silica | - | 5 | 120 | - |
| HPS-C8 | C8 | Yes | 5 | 120 | 11.5 |
| HPS-C18 | C18 | Yes | 5 | 120 | 18.5 |
| HPS-CN | Cyano | No | 5 | 120 | 7.5 |
| HPS-NH2 | Amino | No | 5 | 120 | 4.1 |
| HPS-Phenyl | Phenyl | Yes | 5 | 120 | 12 |
Cogent NP and RP phases
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| NP-Silica | Silica | - | 1.8, 3, 5, 10 | 100 | - |
| NP-Silica | Silica | - | 5, 10 | 300 | - |
| NP-DIOL | DIOL | - | 3, 5, 10 | 100 | 4 |
| NP-DIOL | DIOL | - | 3, 5, 10 | 300 | |
| NP-CN | Cyano | - | 1.8, 3, 5, 10 | 100 | 6 |
| RP-CN | Cyano | - | 1.8, 3, 5, 10 | 100 | 6 |
| RP-CN | Cyano | - | 5, 10 | 300 | 3 |
| NP-NH2 | Amino | - | 1.8, 3, 5, 10 | 100 | 4 |
| NP-NH2 | Amino | - | 3, 5, 10 | 300 | 3 |
| RP-C4 | C4 | - | 1.8, 3, 5, 10 | 100 | 6 |
| RP-C4 | C4 | - | 3, 5, 10 | 300 | 3 |
| RP-C8 | C8 | Yes | 1.8, 3, 5, 10 | 100 | 11 |
| RP-C8 | C8 | No | 3, 5, 10 | 300 | 5 |
| RP-C12 | C12 | Yes | 1.8, 3, 5, 10 | 100 | 16 |
| RP-C18 | C18 | Yes | 1.8, 3, 5, 10 | 100 | 19 |
| RP-C18 | C18 | Yes | 3, 5, 10 | 300 | 8 |
| RP-C18-PE | C18-Amide | Yes | 3, 5, 10 | 100 | 16 |
| RP-C30 | C30 | Yes | 3, 5, 10 | 200 | 19 |
| RP-PFP | Pentafluorophenyl | Yes | 1.8, 3, 5, 10 | 100 | 9 |
| RP-Phenyl | Phenyl | Yes | 1.8, 3, 5, 10 | 100 | 15 |
| RP-Phenyl | Phenyl | Yes | 3, 5, 10 | 300 | 5 |
| RP-Biphenyl | Biphenyl | Yes | 1.8, 3, 5 | 100 | 16 |
| RP-Phenyl-Hexyl | Phenyl-Hexyl | Yes | 1.8, 3, 5, 10 | 100 | 15 |
Cogent IEX (Ion Exchange) phases
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| Cogent IEX SAX | SAX | No | 5, 10 | 100 | 8 |
| Cogent IEX SCX | SCX | No | 5, 10 | 100 | 4 |
| Cogent IEX WAX | WAX | No | 5, 10 | 100 | 11 |
| Cogent IEX WCX | WCX | No | 5, 10 | 100 | 4 |
Cogent Similars - USP Alternate Columns
| Phase | Functional group | Endcapped | Particle, um | Pore, A | Carbon, % |
| Cogent MicroBee HPLC columns match the selectivity of µBondapak | |||||
| MicroBee Silica | Silica | 5, 10 | 125 | ||
| MicroBee CN | Cyano | 5, 10 | 125 | ||
| MicroBee NH2 | Amino | 5, 10 | 125 | ||
| MicroBee C8 | C8 | 5, 10 | 125 | 8 | |
| MicroBee C18 | C18 | 5, 10 | 125 | 10 | |
| MicroBee Phenyl | Phenyl | 5, 10 | 125 | 8 | |
| Cogent Hyper-Similars HPLC columns match the selectivity of Hypersil BDS | |||||
| Hyper-Similars C8 | C8 | 3, 5 | 150 | ||
| Hyper-Similars C18 | C8 | 3, 5 | 150 | ||
| Cogent Nova-Similars HPLC columns match the selectivity of Nova-Pak | |||||
| Nova-Similars C8 | C8 | 4 | 60 | 7 | |
| Nova-Similars C18 | C18 | 4 | 60 | 10 | |
| Nova-Similars Phenyl | Phenyl | 4 | 60 | ||
| Cogent Zx-Similars HPLC columns match the selectivity of Zorbax | |||||
| Zx-Similars C8 | C8 | 3, 5 | 80 | 8 | |
| Zx-Similars C18 | C18 | 3, 5 | 80 | 12 | |
MicroSolv Column Finder
The Excel file below lists all MicroSolv columns with the following parameters: Brand, Phase, Length, Internal diameter, Particle size, Pore size, Surface area, pH range, USP code
HILIC columns vs. Cogent Type-C silica-based columns
Cogent Type-C columns in ANP (Aqueous Normal Phase) mode
outperform HILIC columns in the following areas:
- retain nonpolar compounds by RP mechanism
- retain polar compounds by NP mechanism
- BOTH RP and NP mechanisms can operate simultaneously
- can separate samples with BOTH polar and nonpolar analytes
- equilibration time for gradient elution is 5 minutes between runs
News
Cogent Diamond Hydride column
separates Vancomycin using a simple gradient with water, acetonitrile, and
formic acid.
Vancomycin - retention of a
highly polar antibiotic
Cogent Phenyl Hydride columns:
unique selectivity for compounds with aromatic rings with all the TYPE-C silica
benefits. These columns can be used in RP, ANP or NP mode and changed back and forth
without damage to the columns.
Orthogonal Assay for Fluoxetine
Catalog
Brochures
A new technology that saves you
time and money
Cogent Type-C Silica-Based Bonded
Stationary Phases - Quick Start Instructions
Cogent RP columns: Quick
Ordering Guide
Applications
Pharmaceutical
Applications
Nitrosamines – API or
Impurity Methods for Sartan Drugs
Clinical
Applications
Environmental and
Food
Applications
